skip to main content
US FlagAn official website of the United States government
dot gov icon
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
https lock icon
Secure .gov websites use HTTPS
A lock ( lock ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.


Search for: All records

Creators/Authors contains: "Chen, Xu"

Note: When clicking on a Digital Object Identifier (DOI) number, you will be taken to an external site maintained by the publisher. Some full text articles may not yet be available without a charge during the embargo (administrative interval).
What is a DOI Number?

Some links on this page may take you to non-federal websites. Their policies may differ from this site.

  1. Summary Global food production faces persistent threats from environmental challenges and pathogenic attacks, leading to significant yield losses. Conventional strategies to combat pathogens, such as fungicides and disease‐resistant breeding, are limited by environmental contamination and emergence of pathogen resistance. Herein, we engineered sunlight‐sensitive and biodegradable carbon dots (CDs) capable of generating reactive oxygen species (ROS), offering a novel and sustainable approach for plant protection. Our study demonstrates that CDs function as dual‐purpose materials: priming plant immune responses and serving as broad‐spectrum antifungal agents. Foliar application of CDs generated ROS under light, and the ROS could damage the plant cell wall and trigger cell wall‐mediated immunity. Immune activation enhanced plant resistance against pathogens without compromising photosynthetic efficiency or yield. Specifically, spray treatment with CDs at 240 mg/L (2 mL per plant) reduced the incidence of grey mould inN. benthamianaand tomato leaves by 44% and 12%, respectively, and late blight in tomato leaves by 31%. Moreover, CDs (480 mg/L, 1 mL) combined with continuous sunlight irradiation (simulated by xenon lamp, 9.4 × 105lux) showed a broad‐spectrum antifungal activity. The inhibition ratios for mycelium growth were 66.5% forP. capsici, 8% forS. sclerotiorumand 100% forB. cinerea, respectively. Mechanistic studies revealed that CDs effectively inhibited mycelium growth by damaging hyphae and spore structures, thereby disrupting the propagation and vitality of pathogens. These findings suggest that CDs offer a promising, eco‐friendly strategy for sustainable crop protection, with potential for practical agricultural applications that maintain crop yields and minimize environmental impact. 
    more » « less
    Free, publicly-accessible full text available March 16, 2026
  2. Free, publicly-accessible full text available December 1, 2025
  3. A traffic system can be interpreted as a multiagent system, wherein vehicles choose the most efficient driving approaches guided by interconnected goals or strategies. This paper aims to develop a family of mean field games (MFG) for generic second-order traffic flow models (GSOM), in which cars control individual velocity to optimize their objective functions. GSOMs do not generally assume that cars optimize self-interested objectives, so such a game-theoretic reinterpretation offers insights into the agents’ underlying behaviors. In general, an MFG allows one to model individuals on a microscopic level as rational utility-optimizing agents while translating rich microscopic behaviors to macroscopic models. Building on the MFG framework, we devise a new class of second-order traffic flow MFGs (i.e., GSOM-MFG), which control cars’ acceleration to ensure smooth velocity change. A fixed-point algorithm with fictitious play technique is developed to solve GSOM-MFG numerically. In numerical examples, different traffic patterns are presented under different cost functions. For real-world validation, we further use an inverse reinforcement learning approach (IRL) to uncover the underlying cost function on the next-generation simulation (NGSIM) data set. We formulate the problem of inferring cost functions as a min-max game and use an apprenticeship learning algorithm to solve for cost function coefficients. The results show that our proposed GSOM-MFG is a generic framework that can accommodate various cost functions. The Aw Rascle and Zhang (ARZ) and Light-Whitham-Richards (LWR) fundamental diagrams in traffic flow models belong to our GSOM-MFG when costs are specified. History: This paper has been accepted for the Transportation Science Special Issue on ISTTT25 Conference. Funding: X. Di is supported by the National Science Foundation [CAREER Award CMMI-1943998]. E. Iacomini is partially supported by the Italian Research Center on High-Performance Computing, Big Data and Quantum Computing (ICSC) funded by MUR Missione 4-Next Generation EU (NGEU) [Spoke 1 “FutureHPC & BigData”]. C. Segala and M. Herty thank the Deutsche Forschungsgemeinschaft (DFG) for financial support [Grants 320021702/GRK2326, 333849990/IRTG-2379, B04, B05, and B06 of 442047500/SFB1481, HE5386/18-1,19-2,22-1,23-1,25-1, ERS SFDdM035; Germany’s Excellence Strategy EXC-2023 Internet of Production 390621612; and Excellence Strategy of the Federal Government and the Länder]. Support through the EU DATAHYKING is also acknowledged. This work was also funded by the DFG [TRR 154, Mathematical Modelling, Simulation and Optimization Using the Example of Gas Networks, Projects C03 and C05, Project No. 239904186]. Moreover, E. Iacomini and C. Segala are members of the Indam GNCS (Italian National Group of Scientific Calculus). 
    more » « less
    Free, publicly-accessible full text available November 1, 2025
  4. Free, publicly-accessible full text available November 1, 2025
  5. Mean-field games (MFGs) are developed to model the decision-making processes of a large number of interacting agents in multi-agent systems. This paper studies mean-field games on graphs (G-MFGs). The equilibria of G-MFGs, namely, mean-field equilibria (MFE), are challenging to solve for their high-dimensional action space because each agent has to make decisions when they are at junction nodes or on edges. Furthermore, when the initial population state varies on graphs, we have to recompute MFE, which could be computationally challenging and memory-demanding. To improve the scalability and avoid repeatedly solving G-MFGs every time their initial state changes, this paper proposes physics-informed graph neural operators (PIGNO). The PIGNO utilizes a graph neural operator to generate population dynamics, given initial population distributions. To better train the neural operator, it leverages physics knowledge to propagate population state transitions on graphs. A learning algorithm is developed, and its performance is evaluated on autonomous driving games on road networks. Our results demonstrate that the PIGNO is scalable and generalizable when tested under unseen initial conditions. 
    more » « less
  6. This paper proposes a scalable learning framework to solve a system of coupled forward–backward partial differential equations (PDEs) arising from mean field games (MFGs). The MFG system incorporates a forward PDE to model the propagation of population dynamics and a backward PDE for a representative agent’s optimal control. Existing work mainly focus on solving the mean field game equilibrium (MFE) of the MFG system when given fixed boundary conditions, including the initial population state and terminal cost. To obtain MFE efficiently, particularly when the initial population density and terminal cost vary, we utilize a physics-informed neural operator (PINO) to tackle the forward–backward PDEs. A learning algorithm is devised and its performance is evaluated on one application domain, which is the autonomous driving velocity control. Numerical experiments show that our method can obtain the MFE accurately when given different initial distributions of vehicles. The PINO exhibits both memory efficiency and generalization capabilities compared to physics-informed neural networks (PINNs). 
    more » « less